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 An
over-the-counter diarrhea treatment for humans now
contains an aspirin derivative that in high doses is toxic
to cats, reports the American Veterinary Medical
Association (AVMA).
Kaopectate's new formula contains bismuth subsalicylate,
which may cause salicylate toxicosis in cats that are
overdosed, AVMA says. The product, manufactured by Pfizer,
formerly contained attapulgite, an inert clay aluminum.
Veterinarians have recommended Kaopectate off-label to
treat diarrhea in cats and dogs, particularly for clients
who are unable or unwilling to seek immediate veterinary
care, AVMA officials say.
The range of recommended aspirin-derivative dosages that
have been published for cats is 10 mg/kg every other day
to 25 mg/kg every day, officials add. A tablespoon of
reformulated Kaopectate contains 130 mg aspirin
equivalent, and extra-strength Kaopectate contains
approximately 230 mg aspirin equivalent. A tablespoon of
extra-strength Kaopectate given to a 5-pound cat would
yield approximately 100 mg/kg aspirin equivalent and would
likely result in toxicosis, says Dr. Steve Hansen, a
diplomate of the American Board of Veterinary Toxicology
and director of the American Society for the Prevention of
Cruelty to Animals' Animal Poison Control Center.
Salicylates (e.g. aspirin, Pepto-Bismol and now Kaopectate)
should only be administered to cats under veterinary
supervision. Some dogs are also sensitive to salicylates.
For more information on managing poisons and poison
prevention, visit the ASPCA's Poison Control Center Web
site,
www.apcc.aspca.org.
Information provided by
American
Veterinary Medical Association
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